Lipitor (atorvastatin) is a drug used to lower the levels of blood cholesterol. It can be used to lower the risk of developing heart attack or stroke in people with type 2 diabetes of coronary hart disease. A breakdown in skeletal muscle tissue is a rare yet very serious side effect of taking Lipitor. You will need to watch for any of most probable symptoms of this condition to make sure you can report it to your health care provider as son as any signs become visible. The following symptoms are possible: muscle tenderness, muscle weakness, muscle pain, fever or flu symptoms, and dark-colored urine. To make sure you have been prescribed the lowest most efficient dose (a dose high enough for you to benefit and low enough to avoid serious side effects), make sure you tell your health care provider if you have diabetes, muscle disorder, kidney disease, underactive thyroid, or a history of liver disease, as your dose can depend on some of those factors as well. Your blood and liver function will need to be tested regularly to make sure you benefit from the treatment. The following serious side effects are sometimes possible in patients taking Lipitor, although they are quite rare: muscle weakness, clay-colored stools, loss of appetite, stomach pain, muscle tenderness, muscle pain, low fever, and dark urine. However, you are a lot more likely to get a few mild side effects at the beginning of your treatment, such as mild nausea, constipation, headache, stuffy nose, heartburn, bloating, itching, stomach upset, gas, and skin rash. The mild side effects mentioned usually go away on their own and there is nothing you are supposed to do about them. Make sure you follow other recommendations of your health care provider including those concerning your diet, lifestyle and exercising regularly. An overdose of Lipitor is not expected to produce life-threatening symptoms. However, you will need to seek emergency medical help if you have taken too much of this medicine. Avoid combining any other medications with Lipitor, as this may result in a number of drug interactions. The following medicines should be reported to your doctor before you take the very first dose of Lipitor: gemfibrozil, HIV or AIDS medications, digoxin, cancer medicines, steroids, erythromycin, antifungal medications, and niacin, as well as any other prescription or over-the-counter drugs you may be taking.